Small nucleolar RNA SNORD21

In molecular biology, U21 is a member of the C/D class of snoRNA which contain the C (UGAUGA) and D (CUGA) box motifs. U21 is encoded within an intron of the gene for ribosomal protein L5 in mammals,[1] but within introns of the ADP ribosylation factor gene in Drosophila.[2] U21 snoRNA has a 13 nucleotide region of complementarity with an invariant region of eukaryotic 28S ribosomal RNA.

Small nucleolar RNA SNORD21
Predicted secondary structure and sequence conservation of SNORD21
Identifiers
SymbolSNORD21
Alt. SymbolsU21
RfamRF00068
Other data
RNA typeGene; snRNA; snoRNA; CD-box
Domain(s)Eukaryota
GOGO:0006396 GO:0005730
SOSO:0000593
PDB structuresPDBe

References
  1. Qu LH, Nicoloso M, Michot B, Azum MC, Caizergues-Ferrer M, Renalier MH, Bachellerie JP (October 1994). "U21, a novel small nucleolar RNA with a 13 nt. complementarity to 28S rRNA, is encoded in an intron of ribosomal protein L5 gene in chicken and mammals". Nucleic Acids Research. 22 (20): 4073–81. doi:10.1093/nar/22.20.4073. PMC 331892. PMID 7937132.
  2. Renalier MH, Nicoloso M, Qu LH, Bachellerie JP (February 1996). "SnoRNA U21 is also intron-encoded in Drosophila melanogaster but in a different host-gene as compared to warm-blooded vertebrates". FEBS Letters. 379 (3): 212–6. doi:10.1016/0014-5793(95)01511-6. PMID 8603691. S2CID 28632486.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.