PTGFRN

Prostaglandin F2 receptor negative regulator is a protein that in humans is encoded by the PTGFRN gene.[5][6] PTGFRN has also been designated as CD315 (cluster of differentiation 315).

PTGFRN
Identifiers
AliasesPTGFRN, CD315, CD9P-1, EWI-F, FPRP, SMAP-6, prostaglandin F2 receptor inhibitor
External IDsOMIM: 601204 MGI: 1277114 HomoloGene: 7908 GeneCards: PTGFRN
Orthologs
SpeciesHumanMouse
Entrez

5738

19221

Ensembl

ENSG00000134247

ENSMUSG00000027864

UniProt

Q9P2B2

Q9WV91

RefSeq (mRNA)

NM_020440

NM_011197

RefSeq (protein)

NP_065173

NP_035327

Location (UCSC)Chr 1: 116.91 – 116.99 MbChr 3: 100.95 – 101.02 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

PTGFRN has been shown to interact with CD9[7][8] and CD81.[7][8]

References

  1. GRCh38: Ensembl release 89: ENSG00000134247 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000027864 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Orlicky DJ, Berry R, Sikela JM (Jul 1996). "Human chromosome 1 localization of the gene for a prostaglandin F2alpha receptor negative regulatory protein". Hum Genet. 97 (5): 655–8. doi:10.1007/BF02281878. PMID 8655148. S2CID 21645802.
  6. "Entrez Gene: PTGFRN prostaglandin F2 receptor negative regulator".
  7. Charrin, S; Le Naour F; Oualid M; Billard M; Faure G; Hanash S M; Boucheix C; Rubinstein E (Apr 2001). "The major CD9 and CD81 molecular partner. Identification and characterization of the complexes". J. Biol. Chem. United States. 276 (17): 14329–37. doi:10.1074/jbc.M011297200. ISSN 0021-9258. PMID 11278880.
  8. Stipp, C S; Orlicky D; Hemler M E (Feb 2001). "FPRP, a major, highly stoichiometric, highly specific CD81- and CD9-associated protein". J. Biol. Chem. United States. 276 (7): 4853–62. doi:10.1074/jbc.M009859200. ISSN 0021-9258. PMID 11087758.

Further reading


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