O-774
O-774 is a classical cannabinoid derivative which acts as a potent agonist for the cannabinoid receptors, with a Ki of 0.6 nM at CB1, and very potent cannabinoid effects in animal studies.[1][2]
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Formula | C25H35NO2 |
Molar mass | 381.560 g·mol−1 |
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References
- Singer M, Ryan WJ, Saha B, Martin BR, Razdan RK (October 1998). "Potent cyano and carboxamido side-chain analogues of 1', 1'-dimethyl-delta8-tetrahydrocannabinol". Journal of Medicinal Chemistry. 41 (22): 4400–7. doi:10.1021/jm9803875. PMID 9784115.
- Reggio PH, ed. (2009). "Cannabinoid Receptor Ligands and Structure-Activity Relationships.". The Cannabinoid Receptors. Part I. Humana Press. pp. 6–9. ISBN 978-1-58829-712-9.
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