Haplogroup L6

In human mitochondrial genetics, Haplogroup L6 is a human mitochondrial DNA (mtDNA) haplogroup. It is a small African haplogroup.[3]

Haplogroup L6
Possible time of origin81,500-129,800 YBP[1]
Possible place of originEast Africa
AncestorL3'4'6
DescendantsL6a, L6b
Defining mutations146, 152, 185C, 709, 770, 961, 1461, 4964, 5267, 6002, 6284, 9332, 10978, 11116, 11743, 12771, 13710, 14791, 14959, 5244, 15289, 15499, 16048, 16224[2]

Distribution
Projected spatial frequency distribution for haplogroup L6.
Schematic tree of mtDNA haplogroup L6 (and L4). Ages (in ka) indicated are maximum likelihood estimates obtained for the whole-mtDNA genome.

This haplogroup has been found most often in Yemen and Ethiopia.[4]

Subclades

Tree

This phylogenetic tree of haplogroup M subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[2] and subsequent published research.

  • L3'4'6
    • L6
      • L6a
      • L6b

See also

References
  1. Soares, P; Ermini, L; Thomson, N; Mormina, M; Rito, T; Röhl, A; Salas, A; Oppenheimer, S; et al. (2009). "Correcting for Purifying Selection: An Improved Human Mitochondrial Molecular Clock". American Journal of Human Genetics. 84 (6): 740–59. doi:10.1016/j.ajhg.2009.05.001. PMC 2694979. PMID 19500773.
  2. van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457. S2CID 27566749.
  3. Haplogroups L6.
  4. Abu-Amero, Khaled K; Ana M González (1 Mar 2007). "Eurasian and African mitochondrial DNA influences in the Saudi Arabian population". BMC Evolutionary Biology. 7: 752–770. doi:10.1186/1471-2148-7-32. PMC 1810519. PMID 17331239.
Wikimedia Commons has media related to Haplogroup L6 (mtDNA).

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6  
L1 L2   L3     L4 L5 L6
M N  
CZ D E G Q   O A S R   I W X Y
C Z B F R0   pre-JT   P   U
HV JT K
H V J T
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