HLA-B56
HLA-B56 (B56) is an HLA-B serotype. B56 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B55. The serotype identifies the more common HLA-B*56 gene products.[1] (For terminology help see: HLA-serotype tutorial)
major histocompatibility complex (human), class I, B56 | ||
| Alleles | B*5601, *5602, *5603, *5604 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*5601 | |
| B*5602 | ||
| B*5603 | ||
| B*5604 | ||
| Locus | chr.6 6p21.31 | |
Serotype
| B*56 | B56 | B22 | Sample |
| allele | % | % | size (N) |
| 5601 | 72 | 5 | 671 |
| 5603 | 46 | 8 | 13 |
| 5604 | 73 | 11 |
Allele distribution
| freq | ||
| ref. | Population | (%) |
| [3] | Australian Aborigine Kimberly | 35.5 |
| [3] | Papua New Guinea Madang | 34.6 |
| [3] | Papua New Guinea New Britain Rabaul | 31.6 |
| [3] | Taiwan Ami | 20.4 |
| [3] | New Caledonia | 19.2 |
| [3] | Australian Aborigine Groote Eylandt | 18.0 |
| [3] | Australian Aborigine Cape York Peninsula | 16.5 |
| [3] | Australian Aborigine Yuendumu | 11.4 |
| [3] | China Yunnan Lisu | 9.4 |
| [3] | China Yunnan Nu | 3.8 |
| [3] | Senegal Niokholo Mandenka | 2.7 |
| [3] | Sudanese | 2.5 |
| [3] | American Samoa | 2.0 |
| [3] | China Guangxi Maonan | 1.9 |
| [3] | Taiwan Hakka | 1.8 |
| [3] | Thailand | 1.8 |
| [3] | Finland | 1.7 |
| [3] | Georgia Tbilisi Kurds | 1.7 |
| [3] | India Andhra Pradesh Golla | 1.4 |
| [3] | Croatia | 1.3 |
| [3] | Japan (5) | 1.3 |
| [3] | South Africa Natal Tamil | 1.0 |
| [3] | Taiwan Rukai | 1.0 |
References
- Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- derived from IMGT/HLA
- Middleton, D.; Menchaca, L.; Rood, H.; Komerofsky, R. (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–407. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660.
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