ZC-B

ZC-B (3-(4-bromo-2,5-dimethoxyphenyl)azetidine) is a phenethylamine derivative which acts as a serotonin receptor agonist selective for the 5-HT2 subtypes, with an EC50 of 1.6nM at 5-HT2A, vs 5.8nM at 5-HT2C. It is related to psychedelic phenethylamine derivatives such as 2C-B and mescaline but with the ethylamine side chain replaced by an azetidine ring.[1]

ZC-B
Identifiers
  • 3-(4-bromo-2,5-dimethoxyphenyl)azetidine
CAS Number
PubChem CID
UNII
Chemical and physical data
FormulaC11H14BrNO2
Molar mass272.142 g·mol−1
3D model (JSmol)
  • COC1=CC(=C(C=C1C2CNC2)OC)Br
  • InChI=1S/C11H14BrNO2/c1-14-10-4-9(12)11(15-2)3-8(10)7-5-13-6-7/h3-4,7,13H,5-6H2,1-2H3
  • Key:YFCASESLVDHSAW-UHFFFAOYSA-N

See also

References
  1. US 2021/0137908, Kristensen JL, Jensen AA, Märcher-Rørsted E, "5-HT2A Agonists for Use in Treatment of Depression.", published 13 May 2021, assigned to Lophora ApS.


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