TAS2R60

TAS2R60
Identifiers
Aliases	TAS2R60, T2R56, T2R60, taste 2 receptor member 60
External IDs	OMIM: 613968 MGI: 2681302 HomoloGene: 52230 GeneCards: TAS2R60
Gene location (Human)
Chr.	Chromosome 7 (human)[1]
End	143,444,409 bp[1]
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)[2]
End	42,383,460 bp[2]
RNA expression pattern
	Top expressed in
	mucosa of large intestine; ; blood; ; cell; ; monocyte; ; appendix; ; liver; ; placenta; ; urinary bladder; ; right lobe of liver; ; left uterine tube;
	Top expressed in
	cerebellar cortex;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; bitter taste receptor activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of bitter taste; detection of chemical stimulus involved in sensory perception of bitter taste; signal transduction; response to stimulus; sensory perception of taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	338398
	387512
	ENSG00000185899; ENSG00000285341
	ENSMUSG00000056203
	P59551
	Q7TQA9
	NM_177437
	NM_199159
	NP_803186
	NP_954610
	Wikidata
View/Edit Human	View/Edit Mouse

Taste receptor type 2 member 60 is a protein that in humans is encoded by the TAS2R60 gene.[5][6]

References

ENSG00000285341 GRCh38: Ensembl release 89: ENSG00000185899, ENSG00000285341 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000056203 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Conte C, Ebeling M, Marcuz A, Nef P, Andres-Barquin PJ (Feb 2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family". Cytogenet Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440. S2CID 1542970.
"Entrez Gene: TAS2R60 taste receptor, type 2, member 60".

Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
Shi P, Zhang J, Yang H, Zhang YP (2004). "Adaptive diversification of bitter taste receptor genes in Mammalian evolution". Mol. Biol. Evol. 20 (5): 805–14. doi:10.1093/molbev/msg083. PMID 12679530.
Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-Specific Loss of Function of Bitter Taste Receptor Genes in Humans and Nonhuman Primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

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