SUCNR1

SUCNR1
Identifiers
Aliases	SUCNR1, GPR91, succinate receptor 1
External IDs	OMIM: 606381 MGI: 1934135 HomoloGene: 41865 GeneCards: SUCNR1
Gene location (Human)
Chr.	Chromosome 3 (human)[1]
End	151,884,619 bp[1]
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)[2]
End	59,994,987 bp[2]
RNA expression pattern
	Top expressed in
	cancellous bone; ; bone marrow; ; kidney; ; renal medulla; ; thyroid gland; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; bone marrow cells; ; renal cortex; ; spleen;
	Top expressed in
	white adipose tissue; ; proximal tubule; ; left lobe of liver; ; kidney; ; subcutaneous adipose tissue; ; brown adipose tissue; ; intercostal muscle; ; sciatic nerve; ; mammary gland; ; dermis;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity; signaling receptor activity;
Cellular component	integral component of membrane; plasma membrane; extracellular exosome; membrane;
Biological process	signal transduction; G protein-coupled receptor signaling pathway; renin secretion into blood stream; macrophage activation involved in immune response; interleukin-1 beta production; glucose homeostasis; positive regulation of inflammatory response; positive regulation of chemotaxis; response to calcium ion; regulation of angiotensin metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	56670
	84112
	ENSG00000198829
	ENSMUSG00000027762
	Q9BXA5
	Q99MT6
	NM_033050
	NM_032400
	NP_149039
	NP_115776
	Wikidata
View/Edit Human	View/Edit Mouse

Succinate receptor 1 is a protein that in humans is encoded by the SUCNR1 gene.[5][6][7][8]

References

GRCh38: Ensembl release 89: ENSG00000198829 - Ensembl, May 2017
GRCm38: Ensembl release 89: ENSMUSG00000027762 - Ensembl, May 2017
"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors". J Mol Biol. 307 (3): 799–813. doi:10.1006/jmbi.2001.4520. PMID 11273702.
He W, Miao FJ, Lin DC, Schwandner RT, Wang Z, Gao J, Chen JL, Tian H, Ling L (May 2004). "Citric acid cycle intermediates as ligands for orphan G-protein-coupled receptors". Nature. 429 (6988): 188–93. Bibcode:2004Natur.429..188H. doi:10.1038/nature02488. PMID 15141213.
Macaulay IC, Tijssen MR, Thijssen-Timmer DC, Gusnanto A, Steward M, Burns P, Langford CF, Ellis PD, Dudbridge F, Zwaginga JJ, Watkins NA, van der Schoot CE, Ouwehand WH (Apr 2007). "Comparative gene expression profiling of in vitro differentiated megakaryocytes and erythroblasts identifies novel activatory and inhibitory platelet membrane proteins". Blood. 109 (8): 3260–9. doi:10.1182/blood-2006-07-036269. PMC 6485507. PMID 17192395.
"Entrez Gene: SUCNR1 succinate receptor 1".