Octamoxin

Octamoxin (trade names Ximaol, Nimaol), also known as 2-octylhydrazine, is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine class that was used as an antidepressant in the 1960s but is now no longer marketed.[2][3][4][5]

Octamoxin
Skeletal formula of octamoxin
Names
Preferred IUPAC name
1-Methylheptylhydrazine
Systematic IUPAC name
Octan-2-ylhydrazine[1]
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C8H20N2/c1-3-4-5-6-7-8(2)10-9/h8,10H,3-7,9H2,1-2H3 checkY
    Key: FODQIVGFADUBKE-UHFFFAOYSA-N checkY
  • CCCCCCC(C)NN
Properties
C8H20N2
Molar mass 144.262 g·mol−1
Density 0.831 g/mL
Boiling point 228 °C (442 °F; 501 K)
Pharmacology
Oral
Related compounds
Related compounds
 Tuaminoheptane
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

References
  1. "Octamoxin - Compound Summary". USA: National Center for Biotechnology Information. 26 March 2005. Identification and Related Records. Retrieved 31 May 2012.
  2. Ganellin, C. R.; Triggle, David J. (21 November 1996). Dictionary of pharmacological agents - Google Books. ISBN 9780412466304.
  3. "13-06781. Octamoxin [Archived]: The Merck Index".
  4. Levy J, Michel-Ber E (1966). "[Relations between the antidepressive effects of octamoxine revealed by 3 pharmacological tests and inhibition of cerebral monoamine oxidase in mice]". Thérapie (in French). 21 (4): 929–45. PMID 5925088.
  5. Gayral L, Stern H, Puyuelo R (1966). "[Indications and results of the treatment of mental depression by octamoxine (ximaol)]". Thérapie (in French). 21 (5): 1183–90. PMID 5976767.


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