Mercurophylline

Mercurophylline is a mercurial diuretic, having the form of white or yellow odorless powder under room temperature.[1] It was formerly used as medicine, administered through injection or tablets.[2]

Mercurophylline
Names
IUPAC names
  • Sodium
  • 1,3-dimethyl-7H-purine-2,6-dione
  • mercury(2+)
  • 3-(2-methoxypropylcarbamoyl)-1,2,2-trimethylcyclopentane-1-carboxylate
  • Hydroxide
Other names
  • Mercupurin
  • Mercurin
  • Mercurofilina
  • Mercurophyllinum
  • Novurite
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C14H24NO4.C7H8N4O2.Hg.Na.H2O/c1-9(19-5)8-15-11(16)10-6-7-14(4,12(17)18)13(10,2)3;1-10-5-4(8-3-9-5)6(12)11(2)7(10)13;;;/h9-10H,1,6-8H2,2-5H3,(H,15,16)(H,17,18);3H,1-2H3,(H,8,9);;;1H2/q;;2*+1;/p-2
    Key: NBORQZFOOXTYMX-UHFFFAOYSA-L
  • [Na+].[OH-].[Hg+]CC(OC)CNC(=O)C1CCC(C([O-])=O)(C)C1(C)C.O=C2N(C1NCNC1C(=O)N2C)C
Properties
C21H32HgN5NaO7
Molar mass 690.097 g·mol−1
Appearance Solid
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Mercury poisoning
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Mercurophyllin is poisonous when administered subcutaneously, intraperitoneally and intravenously. When administered intravenously, it can cause cardiac arrhythmia.[3] Prolonged oral administration can lead to gastrointestinal irritation and kidney damage.[4]

References
  1. Hospital Corpsman 3: A Course in Ten Parts with Test Material and Instruction Tests. Bureau of Naval Personnel. 1955. p. 451.
  2. National Formulary. American Pharmaceutical Association. 1970. p. LVII.
  3. PubChem. "Mercurophylline [INN:BAN:NF]". pubchem.ncbi.nlm.nih.gov. Retrieved 2023-06-26.
  4. Association), Council on Drugs (American Medical (1955). New and Nonofficial Remedies. Lippincott. p. 384.
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