Ioxitalamic acid

Ioxitalamic acid (brand name Telebrix) is a pharmaceutical drug used as an iodinated contrast medium for X-ray imaging.[1][2] It is used in form of its salts, ioxitalamate sodium and ioxitalamate meglumine.[3]

Ioxitalamic acid
Skeletal formula of ioxitalamic acid
Space-filling model of the ioxitalamic acid molecule
Clinical data
AHFS/Drugs.comInternational Drug Names
ATC code
Identifiers
  • 3-acetamido-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.044.428
Chemical and physical data
FormulaC12H11I3N2O5
Molar mass643.93955 g·mol−1
3D model (JSmol)
  • CC(=O)NC1=C(C(=C(C(=C1I)C(=O)O)I)C(=O)NCCO)I
  • InChI=1S/C12H11I3N2O5/c1-4(19)17-10-8(14)5(11(20)16-2-3-18)7(13)6(9(10)15)12(21)22/h18H,2-3H2,1H3,(H,16,20)(H,17,19)(H,21,22)
  • Key:OLAOYPRJVHUHCF-UHFFFAOYSA-N

References
  1. Wiggli U (January 1979). "[Clinical study of the tolerance for 2 iodine containing contrast media for computerized tomography of the skull]". Schweizerische Medizinische Wochenschrift. 109 (2): 51–4. PMID 370976.
  2. El-Garawani I, Hassab El-Nabi S, El Kattan A, Sallam A, Elballat S, Abou-Ghanima S, et al. (February 2021). "The Ameliorative Role of Acacia senegal Gum against the Oxidative Stress and Genotoxicity Induced by the Radiographic Contrast Medium (Ioxitalamate) in Albino Rats". Antioxidants. 10 (2): 221. doi:10.3390/antiox10020221. PMC 7912984. PMID 33540787.
  3. International Drug Names: Telebrix. Accessed 2021-03-31.
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