Meglumine

Meglumine is a sugar alcohol derived from glucose that contains an amino group modification. It is often used as an excipient in pharmaceuticals[1] and in conjunction with iodinated compounds in contrast media such as diatrizoate meglumine, iothalamate meglumine, and iodipamide meglumine.[2]

Meglumine
Stereo, skeletal formula of meglumine
Names
Systematic IUPAC name
(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentol
Other names
N-Methyl-D-glucamine; Methylglucamine; N-Methylglucamine; 1-Deoxy-1-(methylamino)-D-glucitol; 1-Deoxy-1-methylaminosorbitol; N-Methylsorbitylamine; Meglumin
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.025.916
UNII
  • InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1 ☒N
    Key: MBBZMMPHUWSWHV-BDVNFPICSA-N ☒N
  • O[C@H]([C@@H](O)CNC)[C@H](O)[C@H](O)CO
Properties
C7H17NO5
Molar mass 195.215 g·mol−1
Appearance White crystals
log P −2.509
Acidity (pKa) 9.52
Basicity (pKb) 0.526
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

See also

References
  1. "Meglumine". Inxight Drugs. National Center for Advancing Translational Sciences.
  2. Meglumine, chemicalland21.com
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