BMY-7378

BMY-7378
Identifiers
	IUPAC name 8-(2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl)-8-azaspiro[4.5]decane-7,9-dione;
CAS Number	21102-95-4 ;
PubChem CID	2419;
IUPHAR/BPS	9;
ChemSpider	2325 ;
UNII	KC07KV8T5O;
ChEMBL	ChEMBL13647;
CompTox Dashboard (EPA)	DTXSID70943430 ;
Chemical and physical data
Formula	C22H31N3O3
Molar mass	385.508 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES C4CCCC4(CC1=O)CC(=O)N1CCN3CCN(CC3)c2ccccc2OC;
	InChI InChI=1S/C22H31N3O3/c1-28-19-7-3-2-6-18(19)24-13-10-23(11-14-24)12-15-25-20(26)16-22(17-21(25)27)8-4-5-9-22/h2-3,6-7H,4-5,8-17H2,1H3 ; Key:AYYCFGDXLUPJAQ-UHFFFAOYSA-N ;
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BMY-7,378 is a 5-HT_1A receptor weak partial agonist/antagonist and α_1D-adrenergic receptor antagonist.[1]

References

Goetz AS, King HK, Ward SD, True TA, Rimele TJ, Saussy DL (January 1995). "BMY 7378 is a selective antagonist of the D subtype of alpha 1-adrenoceptors". European Journal of Pharmacology. 272 (2–3): R5–6. doi:10.1016/0014-2999(94)00751-R. PMID 7713154.

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