Suzanne Pfeffer

Suzanne Ruth Pfeffer is an American neuroscientist who is a professor at Stanford University.[2] Her research investigates the molecular mechanisms that cause receptors to be transported between membrane compartments in cells, and she is an expert in Rab GTPases[3][4][5] and the molecular basis of inherited Parkinson's disease.[1] She is a Fellow of the American Association for the Advancement of Science, American Academy of Arts and Sciences and the American Society for Cell Biology.[6]

Suzanne Pfeffer
Pfeffer in 2010
Born
Suzanne Ruth Pfeffer
Alma materUniversity of California, Berkeley (BS)
University of California, San Francisco (PhD)
Scientific career
FieldsParkinson's disease[1]
InstitutionsStanford University
ThesisThe role of coated vesicles in intracellular transport (1983)
Websiteprofiles.stanford.edu/suzanne-pfeffer

Early life and education

Pfeffer has said that she became interested in human physiology as a child. She was an undergraduate student at the University of California, Berkeley, where she became interested in biochemistry.[7] She worked with Michael Chamberlin on binding of Escherichia coli polymerase to T7 DNA polymerase.[8] She moved to the University of California, San Francisco for her graduate studies, where she worked with Regis B. Kelly on synaptic vessels.[7] Her doctoral research investigated the role of coated vesicles in intracellular transport.[9]

Research and career

After her PhD, she moved to Stanford University as a Hay Whitney postdoctoral fellow, where she worked with James Rothman on Golgi transport.[7][10]

Pfeffer set up her own research program at Stanford University, where she was the first woman to be appointed to the department of biochemistry.[7] Her research investigates the fundamental mechanisms of membrane trafficking.

Selected publications
  • Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi[3]
  • "Rab9 functions in transport between late endosomes and the trans Golgi network[4]
  • Rab GTPases: specifying and deciphering organelle identity and function[5]

Awards and honors

References
  1. Suzanne Pfeffer publications indexed by Google Scholar
  2. Suzanne Pfeffer publications from Europe PubMed Central
  3. Suzanne R. Pfeffer; James E. Rothman (1 January 1987). "Biosynthetic protein transport and sorting by the endoplasmic reticulum and Golgi". Annual Review of Biochemistry. 56: 829–852. doi:10.1146/ANNUREV.BI.56.070187.004145. ISSN 0066-4154. PMID 3304148. Wikidata Q39664981.
  4. D Lombardi; Thierry Soldati; M A Riederer; Y Goda; M Zerial; S R Pfeffer (1 February 1993). "Rab9 functions in transport between late endosomes and the trans Golgi network". The EMBO Journal. 12 (2): 677–682. doi:10.1002/J.1460-2075.1993.TB05701.X. ISSN 0261-4189. PMC 413253. PMID 8440258. Wikidata Q28609814.
  5. Pfeffer SR (December 2001). "Rab GTPases: specifying and deciphering organelle identity and function". Trends in Cell Biology. 11 (12): 487–91. doi:10.1016/S0962-8924(01)02147-X. ISSN 0962-8924. PMID 11719054. Wikidata Q29620750.
  6. profiles.stanford.edu/suzanne-pfeffer
  7. Sedwick, Caitlin (2009-04-06). "Suzanne Pfeffer: Sorting through membrane trafficking". Journal of Cell Biology. 185 (1): 4–5. doi:10.1083/jcb.1851pi. ISSN 1540-8140. PMC 2700508. PMID 19349576.
  8. Pfeffer, S. R.; Stahl, S. J.; Chamberlin, M. J. (1977-08-10). "Binding of Escherichia coli RNA polymerase to T7 DNA. Displacement of holoenzyme from promoter complexes by heparin". The Journal of Biological Chemistry. 252 (15): 5403–5407. ISSN 0021-9258. PMID 328501.
  9. Pfeffer, Suzanne Ruth. The role of coated vesicles in intracellular transport. escholarship.org (PhD thesis). OCLC 1020060429. ProQuest 303125660.
  10. "Suzanne R. Pfeffer, PhD | Parkinson's Disease". michaeljfox.org. Retrieved 2023-07-23.
  11. "ASCB Presidents". ascb.org. Retrieved 2023-07-23.
  12. "Past presidents". asbmb.org. Retrieved 2023-07-23.
  13. "Suzanne Pfeffer". amacad.org. American Academy of Arts & Sciences. 2023-07-23. Retrieved 2023-07-23.
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