Human betaherpesvirus 6A

Human betaherpesvirus 6A (HHV-6A) is a species of virus in the genus Roseolovirus, subfamily Betaherpesvirinae, family Herpesviridae, and order Herpesvirales.[1]

Human betaherpesvirus 6A
Virus classification Edit this classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Orthoherpesviridae
Genus: Roseolovirus
Species:
Human betaherpesvirus 6A
Synonyms

Human herpesvirus 6

Taxonomy

In 1992 the two variants were recognised within Human herpesvirus 6 on the basis of differing restriction endonuclease cleavages, monoclonal antibody reactions,[2] and growth patterns.[3] In 2012 these two variants were officially recognised as distinct species by the International Committee on Taxonomy of Viruses and named Human betaherpesvirus 6A and Human betaherpesvirus 6B.[4] Despite now being recognised as paraphyletic, the name Human herpesvirus 6 still sees usage in clinical contexts.

Pathology
See also: Human herpesvirus 6

Human betaherpesvirus 6A affects humans and includes several adult-derived strains. Its disease spectrum is not well defined, although it is thought by some to be more neurovirulent than Human betaherpesvirus 6B.[5][6]

References
Wikispecies has information related to Human betaherpesvirus 6A.
  1. "ICTV Master Species List 2018b.v2". International Committee on Taxonomy of Viruses (ICTV). Archived from the original on March 30, 2019. Retrieved 19 June 2019.
  2. Kawabata, A.; Oyaizu, H.; Maeki, T.; Tang, H.; Yamanishi, K.; Mori, Y. (2011). "Analysis of a Neutralizing Antibody for Human Herpesvirus 6B Reveals a Role for Glycoprotein Q1 in Viral Entry". Journal of Virology. 85 (24): 12962–71. doi:10.1128/JVI.05622-11. PMC 3233151. PMID 21957287.
  3. Braun, DK; Dominguez, G; Pellett, PE (1997). "Human herpesvirus 6". Clinical Microbiology Reviews. 10 (3): 521–67. doi:10.1128/CMR.10.3.521. PMC 172933. PMID 9227865.
  4. Adams, M. J.; Carstens, E. B. (2012). "Ratification vote on taxonomic proposals to the International Committee on Taxonomy of Viruses (2012)". Archives of Virology. 157 (7): 1411–1422. doi:10.1007/s00705-012-1299-6. PMC 7086667. PMID 22481600.
  5. Kofman, Alexander; Marcinkiewicz, Lucasz; Dupart, Evan; Lyshchev, Anton; Martynov, Boris; Ryndin, Anatolii; Kotelevskaya, Elena; Brown, Jay; et al. (2011). "The roles of viruses in brain tumor initiation and oncomodulation". Journal of Neuro-Oncology. 105 (3): 451–66. doi:10.1007/s11060-011-0658-6. PMC 3278219. PMID 21720806.
  6. Arbuckle, J. H.; Medveczky, M. M.; Luka, J.; Hadley, S. H.; Luegmayr, A.; Ablashi, D.; Lund, T. C.; Tolar, J.; et al. (2010). "The latent human herpesvirus-6A genome specifically integrates in telomeres of human chromosomes in vivo and in vitro". Proceedings of the National Academy of Sciences. 107 (12): 5563–5568. Bibcode:2010PNAS..107.5563A. doi:10.1073/pnas.0913586107. PMC 2851814. PMID 20212114.
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