Adenylylsulfatase
In enzymology, an adenylylsulfatase (EC 3.6.2.1) is an enzyme that catalyzes the chemical reaction
adenylyl sulfate + H2O AMP + sulfate + 2H+
| adenylylsulfatase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.6.2.1 | ||||||||
| CAS no. | 37289-36-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are adenylyl sulfate and H2O, whereas its two products are AMP and sulfate.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides in sulfonyl-containing anhydrides. The systematic name of this enzyme class is adenylyl-sulfate sulfohydrolase. Other names in common use include adenosine 5-phosphosulfate sulfohydrolase, and adenylylsulfate sulfohydrolase. This enzyme participates in sulfur metabolism.
References
- Bailey-Wood R, Dodgson KS, Rose FA (1969). "A rat liver sulphohydrolase enzyme acting on adenylyl sulphate". Biochem. J. 112 (2): 257–8. PMC 1187699. PMID 5801298.
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