Wayne Gretzky Drive

Preceded by 75 Street, Wayne Gretzky Drive starts at 101 Avenue to become a freeway. It crosses the North Saskatchewan River valley, by passing under 106 Avenue and Ada Boulevard. As it approaches Northlands and the Alberta Avenue area, it again returns into an arterial, with traffic lights. The exits to Northlands at 112 Avenue and 116 Avenue are clearly marked with overhead street signs in blue, and with the Northlands logo. Because of property constraints, to maintain the number of lanes, the freeway is divided into Wayne Gretzky Drive Northbound and Southbound, formally 72 Street and 73 Street,[3] at 118 Avenue. 119 Avenue services the north Northlands Coliseum parking lot to the west, and is a dead end to the east, because it was blocked off from being used as a shortcut, disrupting traffic flow during major Northlands events. The northbound and southbound then converge again before crossing the Capital Line of the Edmonton LRT. Fort Road, which runs to the southwest, meets up with Wayne Gretzky Drive at an at-grade intersection, then runs concurrently along with it for approximately 180 metres (590 ft) to Yellowhead Trail. The single-point urban interchange at Yellowhead Trail allows Yellowhead Trail to run as a freeway, and it has the benefit of only one traffic light and U-turns for westbound and eastbound traffic. At this interchange, Wayne Gretzky Drive ends and Fort Road becomes the only road.

Wayne Gretzky Drive and Groat Road are the only freeways in Edmonton not to have provincial highway numbers.

66 Street and 75 Street functions as the southern extension of Wayne Gretzky Drive. It begins as 66 Street at 41 Avenue SW and passes north through Mill Woods, passing by Mill Woods Town Centre, Grey Nuns Community Hospital and Mill Woods Golf Course. At Whitemud Drive the roadway becomes 75 Street and passes through the Southeast Industrial area. North of Argyll Road, 75 Street transitions to passing through mature residential communities. Despite being designated as part of the inner ring road, heavy trucks are prohibited on 75 Street between 90 Avenue and 98 Avenue.[4] At 101 Avenue, 75 Street becomes Wayne Gretzky Drive.

66 Street and 75 Street is part of the southeast alignment of the Valley Line of the Edmonton LRT, which will link Mill Woods with downtown.[5] The LRT will run at-grade, parallel (on the east side) to the roadway between 28 Avenue and Wagner Road, with the exception of an elevated section near Wagner Road as the line will pass over 75 Street and transition to follow 83 Street towards downtown.[6] Stations and stops will be constructed along 66 Street and 75 Street with Grey Nuns stop near 31 Avenue, Millbourne/Woodvale stop near 38 Avenue, and Davies station near Wagner Road; Mill Woods station will east 66 Street along 28 Avenue.[5] As of January 2023, testing was underway on the Valley Line, but the city did not announce a date for opening.[7]

Capilano Bridge takes Wayne Gretzky Drive over the North Saskatchewan River, spanning 290 metres (950 ft).

Grant Moellmann Bridge takes Wayne Gretzky Drive over the LRT tracks and a CN spur that used to service the surrounding industrial area. It was opened in 1995 bridging the gap between 120 Avenue and Fort Road. It is named after Edmontonian ironworker Grant Moellmann (1935–1994) who fell to his death placing the bridge's last girder on November 24, 1994.[8][9] A plaque was placed on the bridge in September 1998 to mark the significance of this naming.