4-Methylphenmetrazine

4-Methylphenmetrazine (mephenmetrazine, 4-MPM, PAL-747) is a recreational designer drug with stimulant effects. It is a substituted phenylmorpholine derivative, closely related to better known drugs such as phenmetrazine and 3-fluorophenmetrazine. It was first identified in Slovenia in 2015,[1][2] and has been shown to act as a monoamine releaser with some preference for serotonin release.[3][4]

4-Methylphenmetrazine
Identifiers
  • 3-methyl-2-(4-methylphenyl)morpholine
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC12H17NO
Molar mass191.274 g·mol−1
3D model (JSmol)
  • CC1C(OCCN1)C2=CC=C(C=C2)C
  • InChI=1S/C12H17NO/c1-9-3-5-11(6-4-9)12-10(2)13-7-8-14-12/h3-6,10,12-13H,7-8H2,1-2H3
  • Key:NWNCIXFIIDVRKE-UHFFFAOYSA-N

See also

References
  1. "Analytical Report. 4-MPH (C12H17NO) 3-methyl-2(p-tolyl)morpholine" (PDF). National Forensic Laboratory. Slovenia. 14 October 2015.
  2. "Europol 2015 Annual Report on the implementation of Council Decision 2005/387/JHA" (PDF). The European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) & Europol.
  3. US 20130203752, Blough BE, Rothman R, Landavazo A, Page KM, Decker AM, "Phenylmorpholines and analogues thereof", published 8 August 2013, issued 11 April 2017, assigned to National Institutes of Health, U.S. Department of Health and Human Services
  4. McLaughlin G, Baumann MH, Kavanagh PV, Morris N, Power JD, Dowling G, et al. (September 2018). "Synthesis, analytical characterization, and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta- positional isomers". Drug Testing and Analysis. 10 (9): 1404–1416. doi:10.1002/dta.2396. PMC 7316143. PMID 29673128.
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