Valerena-4,7(11)-diene synthase
Valerena-4,7(11)-diene synthase (EC 4.2.3.139, VoTPS2) is an enzyme with systematic name (2E,6E)-farnesyl-diphosphate diphosphate-lyase (cyclizing, valerena-4,7(11)-diene-forming).[1] This enzyme catalyses the following chemical reaction
- (2E,6E)-farnesyl diphosphate valerena-4,7(11)-diene + diphosphate
| Valerena-4,7(11)-diene synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.2.3.139 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme is isolated from the plant Valeriana officinalis (valerian).
References
- Pyle BW, Tran HT, Pickel B, Haslam TM, Gao Z, MacNevin G, Vederas JC, Kim SU, Ro DK (September 2012). "Enzymatic synthesis of valerena-4,7(11)-diene by a unique sesquiterpene synthase from the valerian plant (Valeriana officinalis)". The FEBS Journal. 279 (17): 3136–46. doi:10.1111/j.1742-4658.2012.08692.x. PMID 22776156. S2CID 205885638.
External links
- Valerena-4,7(11)-diene+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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