UTP—xylose-1-phosphate uridylyltransferase
In enzymology, an UTP—xylose-1-phosphate uridylyltransferase (EC 2.7.7.11) is an enzyme that catalyzes the chemical reaction
- UTP + alpha-D-xylose 1-phosphate diphosphate + UDP-xylose
| UTP:xylose-1-phosphate uridylyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.7.11 | ||||||||
| CAS no. | 9026-20-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are UTP and alpha-D-xylose 1-phosphate, whereas its two products are diphosphate and UDP-xylose.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing nucleotide groups (nucleotidyltransferases). The systematic name of this enzyme class is UTP:alpha-D-xylose-1-phosphate uridylyltransferase. Other names in common use include xylose-1-phosphate uridylyltransferase, uridylyltransferase, xylose 1-phosphate, UDP-xylose pyrophosphorylase, uridine diphosphoxylose pyrophosphorylase, and xylose 1-phosphate uridylyltransferase. This enzyme participates in nucleotide sugars metabolism.
References
- Ginsburg V, Neufeld EF, Hassid WZ (1956). "Enzymatic Synthesis of Uridine Diphosphate Xylose and Uridine Diphosphate Arabinose". Proc. Natl. Acad. Sci. U.S.A. 42 (6): 333–5. Bibcode:1956PNAS...42..333G. doi:10.1073/pnas.42.6.333. PMC 528284. PMID 16578456.