UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase
In enzymology, an UDP-galactose—UDP-N-acetylglucosamine galactose phosphotransferase (EC 2.7.8.18) is an enzyme that catalyzes the chemical reaction
- UDP-galactose + UDP-N-acetyl-D-glucosamine UMP + UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine
| UDP-galactose-UDP-N-acetylglucosamine galactose phosphotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.8.18 | ||||||||
| CAS no. | 84932-43-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are UDP-galactose and UDP-N-acetyl-D-glucosamine, whereas its two products are UMP and UDP-N-acetyl-6-(D-galactose-1-phospho)-D-glucosamine.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups transferases for other substituted phosphate groups. The systematic name of this enzyme class is UDP-galactose:UDP-N-acetyl-D-glucosamine galactose phosphotransferase. Other names in common use include uridine diphosphogalactose-uridine diphosphoacetylglucosamine galactose-1-phosphotransferase, galactose-1-phosphotransferase, and galactosyl phosphotransferase.
References
- Nakanishi Y, Otsu K, Suzuki S (1983). "Enzymatic transfer of galactosyl phosphate from UDP-galactose to UDP-N-acetylglucosamine". FEBS Lett. 151 (1): 15–8. doi:10.1016/0014-5793(83)80332-9. PMID 6130977.