UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase
UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase (EC 5.1.3.23, UDP-GlcNAc3NAcA 2-epimerase, UDP-alpha-D-GlcNAc3NAcA 2-epimerase, 2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerase, WbpI, WlbD) is an enzyme with systematic name 2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate 2-epimerase.[1][2][3] This enzyme catalyses the following chemical reaction
- UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronate UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-mannuronate
| UDP-2,3-diacetamido-2,3-dideoxyglucuronic acid 2-epimerase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.1.3.23 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
This enzyme participates in the biosynthetic pathway for UDP-alpha-D-ManNAc3NAcA.
References
- Westman EL, McNally DJ, Rejzek M, Miller WL, Kannathasan VS, Preston A, Maskell DJ, Field RA, Brisson JR, Lam JS (July 2007). "Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-alpha-D-glucuronic acid 2-epimerases from respiratory pathogens". The Biochemical Journal. 405 (1): 123–30. doi:10.1042/BJ20070017. PMC 1925246. PMID 17346239.
- Westman, E.L.; McNally, D.J.; Rejzek, M.; Miller, W.L.; Kannathasan, V.S.; Preston, A.; Maskell, D.J.; Field, R.A.; Brisson, J.R.; Lam, J.S. (2007). "Erratum report: Identification and biochemical characterization of two novel UDP-2,3-diacetamido-2,3-dideoxy-α-D-glucuronic acid 2-epimerases from respiratory pathogens". Biochem. J. 405: 625. doi:10.1042/BJ4050625v.
- Sri Kannathasan V, Staines AG, Dong CJ, Field RA, Preston AG, Maskell DJ, Naismith JH (September 2001). "Overexpression, purification, crystallization and data collection on the Bordetella pertussis wlbD gene product, a putative UDP-GlcNAc 2'-epimerase". Acta Crystallographica Section D. 57 (Pt 9): 1310–2. doi:10.1107/s0907444901010885. PMID 11526328.
External links
- UDP-2,3-diacetamido-2,3-dideoxyglucuronic+acid+2-epimerase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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