Trehalose O-mycolyltransferase
In enzymology, a trehalose O-mycolyltransferase (EC 2.3.1.122) is an enzyme that catalyzes the chemical reaction
- 2 alpha,alpha-trehalose 6-mycolate alpha,alpha-trehalose + alpha,alpha-trehalose 6,6'-bismycolate
trehalose O-mycolyltransferase | |||||||||
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Identifiers | |||||||||
EC no. | 2.3.1.122 | ||||||||
CAS no. | 111694-11-2 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Hence, this enzyme has one substrate( alpha,alpha'-trehalose 6-mycolate) and two products ( alpha,alpha-trehalose and alpha,alpha'-trehalose 6,6'-bismycolate).
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is alpha,alpha-trehalose-6-mycolate:alpha,alpha-trehalose-6-mycolate 6'-mycolyltransferase. Other names in common use include alpha,alpha'-trehalose 6-monomycolate:alpha,alpha'-trehalose, mycolyltransferase, alpha,alpha'-trehalose-6-mycolate:alpha,alpha'-trehalose-6-mycolate, and 6'-mycolyltransferase.
References
- Sathyamoorthy N, Takayama K (1987). "Purification and characterization of a novel mycolic acid exchange enzyme from Mycobacterium smegmatis". J. Biol. Chem. 262 (28): 13417–23. PMID 3654621.