Tooth regeneration
Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.[1]
As a source of the new bioengineered teeth, somatic stem cells are collected and reprogrammed to induced pluripotent stem cells which can be placed in the dental lamina directly or placed in a reabsorbable biopolymer[2] in the shape of the new tooth.[3]
History
Young et al.[4] first demonstrated in 2002 that teeth could be regenerated from cells.
See also
References
- Keishi Otsu; Mika Kumakami-Sakano; Naoki Fujiwara; Kazuko Kikuchi; Laetitia Keller; Hervé Lesot; Hidemitsu Harada (February 4, 2014). "Stem cell sources for tooth regeneration: current status and future prospects". Frontiers in Physiology. 5: 36. doi:10.3389/fphys.2014.00036. PMC 3912331. PMID 24550845.
- Biopolymer methods in tissue engineering
- Hill, David J. (2012-05-10). "Toothless no more – Researchers using stem cells to grow new teeth". Singularity Hub. Retrieved June 16, 2014.
- Young CS, Terada S, Vacanti JP, Honda M, Bartlett JD, Yelick PC (2002). "Tissue engineering of complex tooth structures on biodegradable polymer scaffolds". J Dent Res. 81 (10): 695–700. doi:10.1177/154405910208101008. PMID 12351668. S2CID 21891790.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.