Sucrose—1,6-alpha-glucan 3(6)-alpha-glucosyltransferase
In enzymology, a sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase (EC 2.4.1.125) is an enzyme that catalyzes the chemical reaction
- sucrose + (1,6-alpha-D-glucosyl)n D-fructose + (1,6-alpha-D-glucosyl)n+1
| sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.125 | ||||||||
| CAS no. | 81725-87-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are sucrose and (1,6-alpha-D-glucosyl)n, whereas its two products are D-fructose and (1,6-alpha-D-glucosyl)n+1.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is sucrose:1,6-alpha-D-glucan 3(6)-alpha-D-glucosyltransferase. Other names in common use include water-soluble-glucan synthase, GTF-S, sucrose-1,6-alpha-glucan 3(6)-alpha-glucosyltransferase, sucrose:1,6-alpha-D-glucan 3-alpha- and 6-alpha-glucosyltransferase, sucrose:1,6-, 1,3-alpha-D-glucan 3-alpha- and, and 6-alpha-D-glucosyltransferase.
References
- Mukasa H, Shimamura A, Tsumori H (1982). "Purification and characterization of basic glucosyltransferase from Streptococcus mutans serotype c". Biochim. Biophys. Acta. 719 (1): 81–9. doi:10.1016/0304-4165(82)90310-5. PMID 6216919.
- Shimamura A, Tsumori H, Mukasa H (1982). "Purification and properties of Streptococcus mutans extracellular glucosyltransferase". Biochim. Biophys. Acta. 702 (1): 72–80. doi:10.1016/0167-4838(82)90028-0. PMID 6461359.
- Tsumori H, Shimamura A, Mukasa H (1985). "Purification and properties of extracellular glucosyltransferase synthesizing 1,6-, 1,3-alpha-D-glucan from Streptococcus mutans serotype a". J. Gen. Microbiol. 131 (12): 3347–53. doi:10.1099/00221287-131-12-3347. PMID 2937877.