Sphingosine beta-galactosyltransferase
In enzymology, a sphingosine beta-galactosyltransferase (EC 2.4.1.23) is an enzyme that catalyzes the chemical reaction[1]
- UDP-galactose + sphingosine UDP + psychosine
| sphingosine beta-galactosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.23 | ||||||||
| CAS no. | 9032-90-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are UDP-galactose and sphingosine, whereas its two products are UDP and psychosine.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:sphingosine 1-beta-galactosyltransferase. Other names in common use include psychosine-UDP galactosyltransferase, galactosyl-sphingosine transferase, psychosine-uridine diphosphate galactosyltransferase, UDP-galactose:sphingosine O-galactosyl transferase, uridine diphosphogalactose-sphingosine beta-galactosyltransferase, and UDP-galactose:sphingosine 1-beta-galactotransferase. This enzyme participates in sphingolipid metabolism.
References