Savona

• The Cattedrale dell'Assunta (Cathedral of the Assumption), built after Genoese demolition of the old cathedral. It kept the relics of Saint Valentine.
• The Cappella Sistina (Sistine Chapel), adjacent to the cathedral and built 1480–1483, it containing the Mausoleum erected by the Della Rovere Pope Sixtus IV to honor his parents, Leonardo Della Rovere and Luchina Monleone. The construction was commissioned by Giovanni D'Aria and his brother Michele. The chapel is architecturally similar to the chapel dedicated to the Cardinal Pietro Riario in the Basilica of the Santi Apostoli, Rome. After years of deterioration, in 1765-1767 a reconstruction was ordered by the Genovese Doge Francesco Maria Della Rovere. This updated the chapel in a Rococo style, with ceiling painted by Paolo Gerolamo Brusco. The cathedral has a noteworthy 16th-century carved wooden choir seats.
• The church of Nostra Signora di Castello (Our Lady of the Castle) has a large altarpiece by Vincenzo Foppa and Ludovico Brea painted in 1490.
• The Sanctuary of Nostra Signora della Misericordia (Our Lady of Mercy).

• The Torre Leon Pancaldo (Leon Pancaldo Tower), built in the 14th century and also known as "Torretta", is the symbol of the town.
• The Torre del Brandale (Brandale Tower), also known as Campanassa (Commune tower, where the freedom declaration of Savona was signed in 1191) and towers Corsi and Riario.
• The Priamar fortress, built by the Genoese in 1542 after their conquest of Savona, on the area of the old cathedral and old city and later used as a prison and military prison. In 1830-1831 Giuseppe Mazzini was imprisoned in the fortress and he "dreams" the "Giovine Italia". Inside the fortress there is the Museum Centre of Priamar.

• The Palazzo Della Rovere (Della Rovere Palace), built by Cardinal Giulio della Rovere (future Pope Julius II) and designed by Giuliano da Sangallo as a university.
• The Palazzo Gavotti (Gavotti Palace), built in the 15th century. Inside the palace there is the Art Museum of Palazzo Gavotti that contains the Pinacoteca of Savona, the artwork of Fondazione Museo di Arte Contemporanea Milena Milani in memoria di Carlo Cardazzo and the Ceramic Museum.
• The Palazzo Delle Piane (Delle Piane Palace), an important building in Liberty style of Savona.
• The Villa Zanelli, an important Liberty-style former residence and hospital.
• In neighbourhood of Savona remains a house documented as property of Domenico Colombo, father of Christopher Columbus, where they lived for many years (Christopher Columbus lived in Savona for much of his youth).
• The War Memorial, with a marble base and bronze figures, was created by sculptor Luigi Venzano. It was inaugurated on 18 September 1927 and since then every day at 18:00 in Piazza Goffredo Mameli the fallen of all wars are commemorated with 21 tolls of the bell, one for each letter of the Italian alphabet: during the tolling traffic and pedestrians stop as a sign of respect.

• Nemo's Garden is an underwater cultivation[5] project based in nearby Noli, born to face main global issues, such as climate change, pollution, malnourishment and hunger.

Savona has a borderline humid subtropical (Cfa) and Mediterranean climate (Csa).

The average yearly temperature is around 19 °C (66 °F) during the day and 12 °C (54 °F) at night. In the coldest months: January, February and December, the average temperature is 11 °C (52 °F) during the day and 5 °C (41 °F) at night. In the warmest month – July and August – the average temperature is 28 °C (82 °F) during the day and 20 °C (68 °F) at night. Generally, a typical summer season lasts about 4 to 6 months, from May/June to September/October. The daily temperature range is limited, with an average range of about 7 °C (13 °F) between high and low temperatures. Rain occurs mainly in autumn, the summers being generally dry. Sunshine hours total above 2,097 per year, from an average 4 hours of sunshine duration per day in winter to average 9 hours in summer. Savona usually sees snow once or twice per year.