Ptilomycalin A

Ptilomycalin A is an antifungal alkaloid isolated from a marine sponge.[2]

Ptilomycalin A
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
  • InChI=1S/C45H82N6O5.ClH/c1-3-38-24-16-17-28-44(56-38)35-37-26-27-39-41(45(29-21-23-36(2)55-45)49-43(48-44)51(37)39)42(53)54-34-20-14-12-10-8-6-4-5-7-9-11-13-15-25-40(52)50(33-22-31-47)32-19-18-30-46;/h36-39,41H,3-35,46-47H2,1-2H3,(H,48,49);1H/t36-,37+,38+,39-,41-,44+,45-;/m1./s1
    Key: GDECEASHMSFVQR-GYZMTDKTSA-N
  • CC[C@H]1CCCC[C@]2(O1)C[C@@H]3CC[C@H]4[N+]3=C(N2)N[C@]5([C@H]4C(=O)OCCCCCCCCCCCCCCCC(=O)N(CCCCN)CCCN)CCC[C@H](O5)C.[Cl-]
Properties
C45H83ClN6O5
Molar mass 823.65 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Notes
  1. Bycroft, Barrie W.; Payne, David J. (9 August 2013). Dictionary of Antibiotics and Related Substances: with CD-ROM, Second Edition. CRC Press. p. 1460. ISBN 978-1-4822-8215-3.
  2. Dalisay DS, Saludes JP, Molinski TF (2011). "Ptilomycalin A inhibits laccase and melanization in Cryptococcus neoformans". Bioorg Med Chem. 19 (22): 6654–7. doi:10.1016/j.bmc.2011.05.041. PMC 3523195. PMID 21715177.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.