Psychosine sulfotransferase
In enzymology, a psychosine sulfotransferase (EC 2.8.2.13) is an enzyme that catalyzes the chemical reaction:
- 3'-phosphoadenylyl sulfate + galactosylsphingosine adenosine 3',5'-bisphosphate + psychosine sulfate
| psychosine sulfotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.8.2.13 | ||||||||
| CAS no. | 37259-76-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and galactosylsphingosine, whereas its two products are adenosine 3',5'-bisphosphate and psychosine sulfate.
This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:galactosylsphingosine sulfotransferase. Other names in common use include PAPS:psychosine sulphotransferase, and 3'-phosphoadenosine 5'-phosphosulfate-psychosine sulphotransferase.
References
- Nussbaum JL, Mandel P (1972). "Enzymic synthesis of psychosine sulphate". J. Neurochem. 19 (7): 1789–802. doi:10.1111/j.1471-4159.1972.tb06224.x. PMID 5042474.
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