Pregnanetriol
Pregnanetriol, or 5β-pregnane-3α,17α,20α-triol, is a steroid and inactive metabolite of progesterone.
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| Names | |
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| IUPAC name
(20S)-5β-Pregnane-3α,17,20-triol | |
| Systematic IUPAC name
(1R,3aS,3bR,5aR,7R,9aS,9bS,11aS)-1-[(1S)-1-Hydroxyethyl]-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthrene-1,7-diol | |
| Other names
5β-Pregnane-3α,17α,20α-triol | |
| Identifiers | |
3D model (JSmol) |
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| ChemSpider | |
| ECHA InfoCard | 100.012.862 |
PubChem CID |
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| UNII | |
CompTox Dashboard (EPA) |
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| Properties | |
| C21H36O3 | |
| Molar mass | 336.516 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
Urine testing
Urine excretion of pregnanetriol can be measured over a period of 24 hours. Elevated urine pregnanetriol levels suggest adrenogenital syndrome. In monitoring treatment with cortisol replacement, elevated urine pregnanetriol levels indicate insufficient dosage of cortisol.[1]
Reference ranges
For females:[1]
- 0 to 5 years: < 0.1 mg/24 hours
- 6 to 9 years: < 0.3 mg/24 hours
- 10 to 15 years: 0.1 to 0.6 mg/24 hours
- 16 years and older: 0 to 1.4 mg/ 24 hours.
For males:[1]
- 0 to 5 years: < 0.1 mg/24 hours
- 6 to 9 years: < 0.3 mg/24 hours
- 10 to 15 years: 0.2 to 0.6 mg/24 hours
- 16 years and older: 0.2 to 2 mg/ 24 hours
See also
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