Phytanate—CoA ligase
In enzymology, a phytanate—CoA ligase (EC 6.2.1.24) is an enzyme that catalyzes the chemical reaction
- ATP + phytanate + CoA AMP + diphosphate + phytanoyl-CoA
| Phytanate—CoA ligase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 6.2.1.24 | ||||||||
| CAS no. | 105238-50-4 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
The 3 substrates of this enzyme are ATP, phytanate, and CoA, whereas its 3 products are AMP, diphosphate, and phytanoyl-CoA.
This enzyme belongs to the family of ligases, specifically those forming carbon-sulfur bonds as acid-thiol ligases. The systematic name of this enzyme class is phytanate:CoA ligase (AMP-forming). This enzyme is also called phytanoyl-CoA ligase.
References
- Muralidharan FN, Muralidharan VB (1986). "Phytanoyl-CoA ligase activity in rat liver". Biochem. Int. 13 (1): 123–30. PMID 3753503.
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