Phosphoethanolamine N-methyltransferase
In enzymology, a phosphoethanolamine N-methyltransferase (EC 2.1.1.103) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + ethanolamine phosphate S-adenosyl-L-homocysteine + N-methylethanolamine phosphate
| phosphoethanolamine N-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.103 | ||||||||
| CAS no. | 171040-79-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are S-adenosyl methionine and ethanolamine phosphate, whereas its two products are S-adenosylhomocysteine and N-methylethanolamine phosphate.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:ethanolamine-phosphate N-methyltransferase. This enzyme is also called phosphoethanolamine methyltransferase. This enzyme participates in glycerophospholipid metabolism.
References
- Datko AH, Mudd SH (December 1988). "Enzymes of phosphatidylcholine synthesis in lemna, soybean, and carrot". Plant Physiology. 88 (4): 1338–48. doi:10.1104/pp.88.4.1338. PMC 1055762. PMID 16666464.
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