Phosphatidylglycerol—membrane-oligosaccharide glycerophosphotransferase
In enzymology, a phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase (EC 2.7.8.20) is an enzyme that catalyzes the chemical reaction
- phosphatidylglycerol + membrane-derived-oligosaccharide D-glucose 1,2-diacyl-sn-glycerol + membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose
| phosphatidylglycerol-membrane-oligosaccharide glycerophosphotransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.7.8.20 | ||||||||
| CAS no. | 80146-86-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are phosphatidylglycerol and membrane-derived-oligosaccharide D-glucose, whereas its two products are 1,2-diacyl-sn-glycerol and membrane-derived-oligosaccharide 6-(glycerophospho)-D-glucose.
This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups transferases for other substituted phosphate groups. The systematic name of this enzyme class is phosphatidylglycerol:membrane-derived-oligosaccharide-D-glucose glycerophosphotransferase. Other names in common use include phosphoglycerol transferase, oligosaccharide glycerophosphotransferase, and phosphoglycerol transferase I. This enzyme participates in glycerolipid metabolism.
References
- Jackson BJ, Kennedy EP (1983). "The biosynthesis of membrane-derived oligosaccharides. A membrane-bound phosphoglycerol transferase". J. Biol. Chem. 258 (4): 2394–8. PMID 6296144.