PXK
PX domain containing serine/threonine kinase also known as PXK is a protein which in humans is encoded by the PXK gene.[1][2]
| PX domain containing serine/threonine kinase | |||||||
|---|---|---|---|---|---|---|---|
| Identifiers | |||||||
| Symbol | PXK | ||||||
| Alt. symbols | FLJ20335, MONaKA | ||||||
| NCBI gene | 54899 | ||||||
| HGNC | 23326 | ||||||
| OMIM | 611450 | ||||||
| RefSeq | NM_017771 | ||||||
| UniProt | Q6ZN39 | ||||||
| Other data | |||||||
| Locus | Chr. 3 p21.2 | ||||||
| |||||||
Function
PXK binds to the Na⁺/K⁺-ATPase beta-1 (ATP1B1) and beta-3 (ATP1B3) subunits and modulates both Na⁺/K⁺-ATPase enzymatic and ion pump activities.[2]
See also
References
- "Entrez Gene: PX domain containing serine/threonine kinase".
- Mao H, Ferguson TS, Cibulsky SM, Holmqvist M, Ding C, Fei H, Levitan IB (August 2005). "MONaKA, a novel modulator of the plasma membrane Na,K-ATPase". J. Neurosci. 25 (35): 7934–43. doi:10.1523/JNEUROSCI.0635-05.2005. PMC 6725465. PMID 16135750.
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