PTBP2
Polypyrimidine tract binding protein 2, also known as PTBP2, is a protein which in humans is encoded by the PTBP2 gene.[5][6]
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| Aliases | PTBP2, PTBLP, brPTB, nPTB, polypyrimidine tract binding protein 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 608449 MGI: 1860489 HomoloGene: 23162 GeneCards: PTBP2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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Function
The protein encoded by this gene binds to the intronic cluster of RNA regulatory elements, downstream control sequence (DCS). It is implicated in controlling the assembly of other splicing-regulatory proteins. This protein is very similar to the polypyrimidine tract-binding protein PTBP1 but it is expressed primarily in the brain.[6]
References
- GRCh38: Ensembl release 89: ENSG00000117569 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000028134 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Markovtsov V, Nikolic JM, Goldman JA, Turck CW, Chou MY, Black DL (October 2000). "Cooperative assembly of an hnRNP complex induced by a tissue-specific homolog of polypyrimidine tract binding protein". Mol. Cell. Biol. 20 (20): 7463–79. doi:10.1128/MCB.20.20.7463-7479.2000. PMC 86300. PMID 11003644.
- "Entrez Gene: PTBP2 polypyrimidine tract binding protein 2".
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