PPP6C

Serine/threonine-protein phosphatase 6 catalytic subunit is an enzyme that in humans is encoded by the PPP6C gene.[5][6]

PPP6C
Identifiers
AliasesPPP6C, PP6, PP6C, protein phosphatase 6 catalytic subunit
External IDsOMIM: 612725 MGI: 1915107 HomoloGene: 68273 GeneCards: PPP6C
Orthologs
SpeciesHumanMouse
Entrez

5537

67857

Ensembl

ENSG00000119414

ENSMUSG00000026753

UniProt

O00743

Q9CQR6

RefSeq (mRNA)

NM_001123355
NM_001123369
NM_002721

NM_024209

RefSeq (protein)

NP_001116827
NP_001116841
NP_002712

NP_077171

Location (UCSC)Chr 9: 125.15 – 125.19 MbChr 2: 39.08 – 39.12 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse


Interactions

PPP6C has been shown to interact with IGBP1.[7][8]

References

  1. GRCh38: Ensembl release 89: ENSG00000119414 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000026753 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Bastians H, Krebber H, Vetrie D, Hoheisel J, Lichter P, Ponstingl H, Joos S (April 1997). "Localization of the novel serine/threonine protein phosphatase 6 gene (PPP6C) to human chromosome Xq22.3". Genomics. 41 (2): 296–7. doi:10.1006/geno.1997.4640. PMID 9143513.
  6. "Entrez Gene: PPP6C protein phosphatase 6, catalytic subunit".
  7. Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, et al. (November 2005). "A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity". Molecular & Cellular Proteomics. 4 (11): 1725–40. doi:10.1074/mcp.M500231-MCP200. PMID 16085932.
  8. Chen J, Peterson RT, Schreiber SL (June 1998). "Alpha 4 associates with protein phosphatases 2A, 4, and 6". Biochemical and Biophysical Research Communications. 247 (3): 827–32. doi:10.1006/bbrc.1998.8792. PMID 9647778.

Further reading


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