POPC

POPC is a phosphatidylcholine. It is a diacylglycerol and phospholipid. The full name is 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine. It is an important phospholipid for biophysical experiments and has been used to study various subjects such as lipid rafts. POPC is also used in systems mimicking the cell membrane such as Nanodiscs.[1] It is available commercially synthetically[2] and is naturally present in eukaryotic cell membranes.

POPC
Names
Systematic IUPAC name
(2R)-3-(Hexadecanoyloxy)-2-{[(9Z)-octadec-9-enoyl]oxy}propyl 2-(trimethylazaniumyl)ethyl phosphate
Other names
1-Palmitoyl-2-oleoylphosphatidylcholine, palmitoyloleoylphosphatidylcholine
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.043.673
UNII
  • InChI=1S/C42H82NO8P/c1-6-8-10-12-14-16-18-20-21-23-25-27-29-31-33-35-42(45)51-40(39-50-52(46,47)49-37-36-43(3,4)5)38-48-41(44)34-32-30-28-26-24-22-19-17-15-13-11-9-7-2/h20-21,40H,6-19,22-39H2,1-5H3/b21-20-/t40-/m1/s1 checkY
    Key: WTJKGGKOPKCXLL-VYOBOKEXSA-N checkY
  • CCCCCCCCCCCCCCCC(=O)OC[C@H](COP(=O)([O-])OCC[N+](C)(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC
Properties
C42H82NO8P
Molar mass 760.091 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
This article is about the chemical. For the population count CPU instruction, see Hamming weight.

References
  1. Stephen G. Sligar. "Nanodisc Technology: Soluble Lipid Bilayer Systems for Structural and Functional Studies of Membrane Proteins".
  2. "AVANTI Polar Lipids".
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