PABPC5

Poly(A) binding protein cytoplasmic 5 is a protein that in humans is encoded by the PABPC5 gene. [5]

PABPC5
Identifiers
AliasesPABPC5, PABP5, poly(A) binding protein cytoplasmic 5
External IDsOMIM: 300407 MGI: 2136401 HomoloGene: 5857 GeneCards: PABPC5
Orthologs
SpeciesHumanMouse
Entrez

140886

93728

Ensembl

ENSG00000174740

ENSMUSG00000034732

UniProt

Q96DU9

Q8C7D3

RefSeq (mRNA)

NM_080832

NM_053114

RefSeq (protein)

NP_543022

NP_444344

Location (UCSC)Chr X: 91.43 – 91.44 MbChr X: 118.84 – 118.84 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a poly(A)-binding protein that binds to the polyA tail found at the 3' end of most eukaryotic mRNAs. It is thought to play a role in the regulation of mRNA metabolic processes in the cytoplasm. This gene is located in a gene-poor region within the X-specific 13d-sY43 subinterval of the chromosome Xq21.3/Yp11.2 homology block. It is located close to translocation breakpoints associated with premature ovarian failure, and is therefore a potential candidate gene for this disorder. [provided by RefSeq, May 2010].

References
  1. GRCh38: Ensembl release 89: ENSG00000174740 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000034732 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Poly(A) binding protein cytoplasmic 5". Retrieved 2020-04-16.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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