N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase
In enzymology, a N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase (EC 2.4.1.188) is an enzyme that catalyzes the chemical reaction
- UDP-glucose + N-acetyl-D-glucosaminyldiphosphoundecaprenol UDP + beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol
| N-acetylglucosaminyldiphosphoundecaprenol glucosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.4.1.188 | ||||||||
| CAS no. | 118731-83-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are UDP-glucose and N-acetyl-D-glucosaminyldiphosphoundecaprenol, whereas its two products are UDP and beta-D-glucosyl-1,4-N-acetyl-D-glucosaminyldiphosphoundecaprenol.
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-glucose:N-acetyl-D-glucosaminyldiphosphoundecaprenol 4-beta-D-glucosyltransferase. Other names in common use include UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol, glucosyltransferase, uridine, diphosphoglucose-acetylglucosaminylpyrophosphorylundecaprenol, and glucosyltransferase.
References
- Kumita K, Murazumi N, Araki Y, Ito E (December 1988). "Solubilization and properties of UDP-D-glucose:N-acetylglucosaminyl pyrophosphorylundecaprenol glucosyltransferase from Bacillus coagulans AHU 1366 membranes". J. Biochem. Tokyo. 104 (6): 985–8. PMID 2977388.