Macromomycin B

Macromomycin B is an antibiotic with anticancer activity.[1]

Macromomycin B
Names
Preferred IUPAC name
Methyl 7-methoxy-2-methylidene-3-oxo-3,4-dihydro-2H-1,4-benzoxazine-5-carboxylate
Other names
Auromomycin
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C12H11NO5/c1-6-11(14)13-10-8(12(15)17-3)4-7(16-2)5-9(10)18-6/h4-5H,1H2,2-3H3,(H,13,14)
    Key: HXKWEZFTHHFQMB-UHFFFAOYSA-N
  • InChI=1/C12H11NO5/c1-6-11(14)13-10-8(12(15)17-3)4-7(16-2)5-9(10)18-6/h4-5H,1H2,2-3H3,(H,13,14)
    Key: HXKWEZFTHHFQMB-UHFFFAOYAU
  • O=C(OC)c2cc(OC)cc1O/C(C(=O)Nc12)=C
Properties
C12H11NO5
Molar mass 249.219
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Lippman, MM; Laster, WR; Abbott, BJ; Venditti, J; Baratta, M (April 1975). "Antitumor activity of macromomycin B (NSC 170105) against murine leukemias, melanoma, and lung carcinoma". Cancer Research. 35 (4): 939–45. PMID 1116151.


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