MYL12B

Myosin, light chain 12B, regulatory is a protein that in humans is encoded by the MYL12B gene.[1] The gene is also known as MLC-B and MRLC2.[1] The activity of nonmuscle myosin II is regulated by phosphorylation of a regulatory light chain, such as MYL12B. This phosphorylation results in higher ATPase activity and the assembly of myosin II filaments.[1][2]

References
  1. "Myosin, light chain 12B, regulatory". Retrieved 2011-12-05.
  2. Iwasaki, T.; Murata-Hori, M.; Ishitobi, S.; Hosoya, H. (2001). "Diphosphorylated MRLC is required for organization of stress fibers in interphase cells and the contractile ring in dividing cells". Cell Structure and Function. 26 (6): 677–683. doi:10.1247/csf.26.677. PMID 11942626.

Further reading
  • Li, T. B.; Liu, X. H.; Feng, S.; Hu, Y.; Yang, W. X.; Han, Y.; Wang, Y. G.; Gong, L. M. (2004). "Characterization of MR-1, a novel myofibrillogenesis regulator in human muscle". Acta Biochimica et Biophysica Sinica. 36 (6): 412–418. doi:10.1093/abbs/36.6.412. PMID 15188056. S2CID 18331104.


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.