MICAL3

Microtubule-associated monoxygenase, calponin and LIM domain containing 3, also known as MICAL3, is a human gene.[5]

MICAL3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMICAL3, MICAL-3, microtubule associated monooxygenase, calponin and LIM domain containing 3
External IDsOMIM: 608882 MGI: 2442733 HomoloGene: 85288 GeneCards: MICAL3
Orthologs
SpeciesHumanMouse
Entrez

57553

194401

Ensembl

ENSG00000243156

ENSMUSG00000051586

UniProt

Q7RTP6

Q8CJ19

RefSeq (mRNA)

NM_001122731
NM_001136004
NM_015241
NM_020793

NM_001270475
NM_153396

RefSeq (protein)

NP_001116203
NP_001129476
NP_056056

NP_001257404
NP_700445

Location (UCSC)Chr 22: 17.79 – 18.02 MbChr 6: 120.93 – 121.13 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Along with two other Rab proteins, Rab6 and Rab8, MICAL3 work together in the process of docking and fusing of vesicles that are involved in exocytosis.[6]

References

  1. GRCh38: Ensembl release 89: ENSG00000243156 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000051586 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: MICAL3 microtubule associated monoxygenase, calponin and LIM domain containing 3".
  6. Grigoriev I, Yu KL, Martinez-Sanchez E, Serra-Marques A, Smal I, Meijering E, et al. (June 2011). "Rab6, Rab8, and MICAL3 cooperate in controlling docking and fusion of exocytotic carriers". Current Biology. 21 (11): 967–974. doi:10.1016/j.cub.2011.04.030. PMID 21596566. S2CID 7950950.

Further reading


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