MED10

Mediator complex subunit 10 (Med10) is a protein that in humans is encoded by the MED10 gene.[5]

MED10
Identifiers
AliasesMED10, NUT2, TRG20, L6, mediator complex subunit 10
External IDsOMIM: 612382 MGI: 106331 HomoloGene: 44533 GeneCards: MED10
Orthologs
SpeciesHumanMouse
Entrez

84246

28077

Ensembl

ENSG00000133398

ENSMUSG00000021598

UniProt

Q9BTT4

Q9CXU0

RefSeq (mRNA)

NM_032286

NM_138596
NM_001378925

RefSeq (protein)

NP_115662

NP_613062
NP_001365854

Location (UCSC)Chr 5: 6.37 – 6.38 MbChr 13: 69.95 – 69.96 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

Med10 is a component of the Mediator complex, which is a coactivator for DNA-binding factors that activate transcription via RNA polymerase II.[6][supplied by OMIM, Oct 2008].

See also

References

  1. GRCh38: Ensembl release 89: ENSG00000133398 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000021598 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Mediator complex subunit 10".
  6. Sato S, Tomomori-Sato C, Banks CA, Sorokina I, Parmely TJ, Kong SE, et al. (April 2003). "Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3". The Journal of Biological Chemistry. American Society for Biochemistry & Molecular Biology (ASBMB). 278 (17): 15123–7. doi:10.1074/jbc.c300054200. PMID 12584197.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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