M. Lisa Manning

Mary Lisa Manning (born 1980) is an American physicist and the William R. Kenan, Jr., Professor[1] of Physics at Syracuse University in Syracuse, New York, United States. Manning's research focuses on the behavior of glassy materials, using simulations and theory to model the emergent properties of biological tissues.

M. Lisa Manning
Born(1980-09-05)September 5, 1980
Cincinnati, Ohio, United States
NationalityAmerican
SpouseWilliam Wylie
AwardsSloan Research Fellowship
Simons Investigators Award
Maria Goeppert-Mayer Award
Scientific career
ThesisEffective temperature and strain localization in amorphous solids (2004)
Doctoral advisorJean Carlson
Websitehttps://mmanning.expressions.syr.edu

Background

Manning grew up in a suburb of Cincinnati, Ohio and attended the University of Virginia as a Jefferson Scholar, graduating in 2002 with bachelor's degrees in physics and mathematics.[2] She earned a Ph.D. in physics from the University of California at Santa Barbara in 2008, followed by a postdoctoral fellowship at the Princeton University Center for Theoretical Science. In 2011, Manning accepted a faculty position at Syracuse University. In 2020, Manning was named the William R. Kenan, Jr., Professor[1] of Physics at the same university.

Manning is married to William Wylie and has two children.

Research

As a graduate student, Manning studied the behaviors and properties of disordered solids and glasses under the mentorship of Jean Carlson. Among other findings, she described how effective temperature is an important determinant of material failure and strain localization, with potential applications for a wide range of amorphous materials.[3]

After earning her Ph.D., Manning expanded her research on amorphous and granular solids to include biological cells, noting that many types of tissues behave as though they were glassy solids.[4] Manning has developed a model describing the relationship between cell adhesion and cortical tension as a determinant for embryonic surface tension.[5] Her ongoing research modeling the relationship between cell shape and jamming leading to tissue rigidity has implications for cell migration in metastatic cancer, wound healing, embryogenesis, and asthma.[6][7][8][9][10] In addition, Manning has continued to explore the dynamics of conventional disordered solids.[11][12][13] In 2018, Manning was named by Science News as one of 2018's 10 scientists to watch.[14]

Honors and awards

References
  1. "M. Lisa Manning, professor of physics and founding director of BioInspired Syracuse: Institute for Material and Living Systems, has been named the William R. Kenan, Jr., Professor of Physics. This highly selective professorship was established in 1971 by". College of Arts & Sciences at Syracuse University. Retrieved 2020-06-22.
  2. "Lisa Manning - Jefferson Scholars Foundation". www.jeffersonscholars.org.
  3. Effective temperature and strain localization in amorphous solids (PhD thesis). University of California, Santa Barbara. ISBN 9780549842576. Retrieved 2022-09-01.
  4. "The Physics of Glass Opens a Window Into Biology - Quanta Magazine". 11 June 2018.
  5. Manning, M. Lisa; Foty, Ramsey A.; Steinberg, Malcolm S.; Schoetz, Eva-Maria (13 July 2010). "Coaction of intercellular adhesion and cortical tension specifies tissue surface tension". Proceedings of the National Academy of Sciences. 107 (28): 12517–12522. Bibcode:2010PNAS..10712517M. doi:10.1073/pnas.1003743107. PMC 2906578. PMID 20616053.
  6. Merkel, Matthias; Manning, Lisa (2017). "A geometrically controlled rigidity transition in a model for confluent 3D tissues". New Journal of Physics. 20 (2): 022002. arXiv:1706.02656. doi:10.1088/1367-2630/aaaa13. S2CID 3867697.
  7. Merkel, Matthias; Manning, Lisa; Schwarz, J. M; Manning, M. Lisa (2013). "Energy barriers govern glassy dynamics in tissues". Soft Matter. 10 (12): 1885–90. arXiv:1308.3891. doi:10.1039/c3sm52893f. PMID 24652538.
  8. Amack, Jeffrey D.; Manning, M. Lisa (12 October 2012). "Knowing the Boundaries: Extending the Differential Adhesion Hypothesis in Embryonic Cell Sorting". Science. 338 (6104): 212–215. Bibcode:2012Sci...338..212A. doi:10.1126/science.1223953. PMID 23066072. S2CID 206542264.
  9. Yang, Xingbo; Bi, Dapeng; Czajkowski, Michael; Merkel, Matthias; Manning, M. Lisa; Marchetti, M. Cristina (28 November 2017). "Correlating cell shape and cellular stress in motile confluent tissues". Proceedings of the National Academy of Sciences. 114 (48): 12663–12668. arXiv:1704.05951. Bibcode:2017PNAS..11412663Y. doi:10.1073/pnas.1705921114. PMC 5715741. PMID 29138312.
  10. "Jammed Cells Expose the Physics of Cancer". Quanta Magazine. 16 August 2016.
  11. Merkel, Matthias; Manning, Lisa (2015). "Disentangling defects and sound modes in disordered solids". arXiv:1502.00685 [cond-mat.soft].
  12. Merkel, Matthias; Manning, Lisa; Porter, M. A; Manning, M. L; Daniels, K. E (2015). "Extraction of Force-Chain Network Architecture in Granular Materials Using Community Detection". Soft Matter. 11 (14): 2731–44. arXiv:1408.3841. Bibcode:2015SMat...11.2731B. doi:10.1039/c4sm01821d. PMID 25703651. S2CID 18154269.
  13. Merkel, Matthias; Manning, Lisa (2015). "A random matrix definition of the boson peak". EPL. 109 (36002): 36002. arXiv:1307.5904. Bibcode:2015EL....10936002M. doi:10.1209/0295-5075/109/36002. S2CID 21737384.
  14. Cunningham, Aimee (28 September 2018). "Lisa Manning describes the physics of how cells move".
  15. "Materials, like metallic glass, can help us understand how cells break - NSF - National Science Foundation". www.nsf.gov.
  16. "Immersive DNA force sensors and predictive mechanical modeling for tissue morphogenesis - Scialog: Collaborative Teams - Research Corporation for Science Advancement". Research Corporation for Science Advancement.
  17. "M. Lisa Manning - Cottrell Scholar Awards - Research Corporation for Science Advancement". Research Corporation for Science Advancement.
  18. "Lisa Manning - Simons Foundation". Simons Foundation. 13 July 2017.
  19. "C3: News - IUPAP: The International Union of Pure and Applied Physics". iupap.org. 8 March 2021.
  20. "2018 Stanley Corrsin Award Recipient". www.aps.org.
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