Johann Conrad Brunner

Brunner was born in Diessenhofen,[2] and studied medicine in Schaffhausen, Strasbourg, Amsterdam, London and Paris. At Schaffhausen he studied under Johann Jakob Wepfer (1620–1695), who was also his father-in-law. He received his doctorate in 1672 from the University of Strasbourg.[2] Beginning in 1686 he was a professor of anatomy and physiology at the University of Heidelberg.[2] In 1716, Brunner was appointed personal physician to Charles III Philip the new Elector of the Palatinate.[2] He received many accolades during his life including a knighthood with the title "Brunn von Hammerstein".[2] He died in 1727 in Mannheim, Germany.[1]

Brunner is remembered for his experiments and studies of the pancreas and the internal secretions associated with that organ. In 1683 he removed the pancreas from a dog and noticed that the animal experienced extreme thirst and polyuria. Despite his intuitive grasp of the connection between the pancreas and diabetes, he was unable to provide a theoretical link for the role of the pancreas in that disease. He published his findings on pancreatic research in a treatise titled Experimenta Nova circa Pancreas. Accedit diatribe de lympha & genuino pancreatis usu.

in 1687 he described tubuloalveolar glands in the submucous layer of the duodenum, which were later named Brunner's glands. Two disorders associated with these glands are:

• "Brunner's gland hyperplasia": Hypertrophy of Brunner's glands in the submucosal layer of the duodenum.
• "Brunner's gland adenoma": Polyp-like tumours arising from Brunner's glands.

• Description of Experimenta Nova circa Pancreas
• Diabetes, Doctors and Dogs
• List of publications copied from the German Wikipedia.