Hydroxypyruvate decarboxylase
The enzyme hydroxypyruvate decarboxylase (EC 4.1.1.40) catalyzes the chemical reaction
- hydroxypyruvate glycolaldehyde + CO2
| hydroxypyruvate decarboxylase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 4.1.1.40 | ||||||||
| CAS no. | 37289-43-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
This enzyme belongs to the family of lyases, specifically the carboxy-lyases, which cleave carbon-carbon bonds. The systematic name of this enzyme class is hydroxypyruvate carboxy-lyase (glycolaldehyde-forming). This enzyme is also called hydroxypyruvate carboxy-lyase. This enzyme participates in glyoxylate and dicarboxylate metabolism.
References
- HEDRICK JL, SALLACH HJ (1964). "THE NONOXIDATIVE DECARBOXYLATION OF HYDROXYPYRUVATE IN MAMMALIAN SYSTEMS". Arch. Biochem. Biophys. 105 (2): 261–9. doi:10.1016/0003-9861(64)90007-4. PMID 14186730.
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