Gutolactone

Gutolactone is a chemical compound extracted from Simaba guianensis and it has displayed antimalarial properties in vitro.[1]

Gutolactone
Names
Other names
Gurolactone
Identifiers
3D model (JSmol)
ChEBI
  • InChI=1S/C25H32O9/c1-10(2)6-15(27)34-17-19-24(5)21(30)16(28)18-23(4)12(11(3)7-13(26)20(23)29)8-14(33-22(17)31)25(18,19)9-32-24/h6-7,12,14,16-21,28-30H,8-9H2,1-5H3/t12-,14+,16+,17+,18+,19-,20+,21-,23-,24-,25+/m0/s1
    Key: WSUNNCJENRRPLS-DQVMPRLHSA-N
  • CC1=CC(=O)[C@H]([C@]2([C@H]1C[C@@H]3[C@]45[C@@H]2[C@H]([C@@H]([C@]([C@@H]4[C@H](C(=O)O3)OC(=O)C=C(C)C)(OC5)C)O)O)C)O
Properties
C25H32O9
Molar mass 476.522 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Cabral, Jose A; McChesney, James D; Milhous, Wilbur K (1993). "A New Antimalarial Quassinoid from Simaba guianensis". Journal of Natural Products. 56 (11): 1954–61. doi:10.1021/np50101a014. PMID 8289064.
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