Monolaurin

Monolaurin (abbreviated GML; also called glycerol monolaurate, glyceryl laurate, and 1-lauroyl-glycerol) is a monoglyceride. It is the mono-ester formed from glycerol and lauric acid. Its chemical formula is C15H30O4.

Monolaurin
Names
IUPAC name
2,3-Dihydroxypropyl dodecanoate
Other names
Glyceryl laurate; Monolauroylglycerin; Glycerol monolaurate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.005.024
UNII
  • InChI=1S/C15H30O4/c1-2-3-4-5-6-7-8-9-10-11-15(18)19-13-14(17)12-16/h14,16-17H,2-13H2,1H3 checkY
    Key: ARIWANIATODDMH-UHFFFAOYSA-N checkY
  • InChI=1/C15H30O4/c1-2-3-4-5-6-7-8-9-10-11-15(18)19-13-14(17)12-16/h14,16-17H,2-13H2,1H3
    Key: ARIWANIATODDMH-UHFFFAOYAD
  • OCC(O)COC(=O)CCCCCCCCCCC
Properties
C15H30O4
Molar mass 274.401 g·mol−1
Melting point 63 °C
Boiling point 186 °C / 1mmHg
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Occurrence

Monolaurin is found in coconut oil and may be similar to other monoglycerides found in human breast milk.[1]

Lauric acid can be ingested in coconut oil and the human body converts it into monolaurin. Furthermore, coconut oil, coconut cream, grated coconut and others products are sources of lauric acid and, consequently, monolaurin.[2]

Uses

Monolaurin is most commonly used as a surfactant in cosmetics, such as deodorants. As a food additive it is also used as an emulsifier or preservative. Monolaurin is also marketed as a dietary supplement.

Monolaurin in capsule form as a dietary supplement

Monolaurin is sold as a dietary supplement and as an ingredient in certain foods. The United States Food and Drug Administration categorizes it as generally recognized as safe.[3]

References
  1. Hegde, BM (2006). "View Point: Coconut Oil – Ideal Fat next only to Mother's Milk (Scanning Coconut's Horoscope)" (PDF). Journal of the Indian Academy of Clinical Medicine. 7: 16–19.
  2. Lieberman, S.; Enig, M. G.; Preuss, H. G. (2006). "A Review of Monolaurin and Lauric Acid: Natural Virucidal and Bactericidal Agents". Alternative and Complementary Therapies. 12 (6): 310–314. doi:10.1089/act.2006.12.310.
  3. "Code of Federal Regulations title 21". www.accessdata.fda.gov.
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