Dipeptidase 2
Dipeptidase 2 (DPEP2) is a protein which in humans is encoded by the DPEP2 gene.[4]
DPEP2 | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Aliases | DPEP2, MBD2, dipeptidase 2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 609925 MGI: 2442042 HomoloGene: 49703 GeneCards: DPEP2 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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DPEP2 belongs to the membrane-bound dipeptidase (EC 3.4.13.19) family. These enzymes hydrolyze a variety of dipeptides, including leukotriene D4, the beta-lactam ring of some antibiotics, and cystinyl-bis-glycine (cys-bis-gly) formed during glutathione degradation.[5]
References
- GRCh38: Ensembl release 89: ENSG00000167261 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- Habib GM, Shi ZZ, Cuevas AA, Lieberman MW (July 2003). "Identification of two additional members of the membrane-bound dipeptidase family". The FASEB Journal. 17 (10): 1313–5. doi:10.1096/fj.02-0899fje. PMID 12738806. S2CID 15252871.
- "Entrez Gene: Dipeptidase 2".
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