Dibenzoylhydrazine

Dibenzoylhydrazine (DBH) is a synthetic chemical compound with the chemical formulation C14H12N2O2. It is sometimes known as a benzoic acid amine, and is related to benzoyl peroxide, tricarban, isocarboxazid, and hydrazine. The substance was patented as an "ecdysone receptor ligand-binding domain structure" on 9 December 2004 by Michael C. Lawrence and nine others at the Australian CSIRO,[1] and since 1991 it had been known to be effective in compound form against insect pests of the orders Lepidoptera, Coleoptera, and Hemiptera.[2]

Dibenzoylhydrazine
Names
Preferred IUPAC name
N′-Benzoylbenzohydrazide
Other names
1,2-Dibenzoylhydrazine
Identifiers
3D model (JSmol)
523810
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.011.209
EC Number
  • 212-329-9
281733
UNII
  • InChI=1S/C14H12N2O2/c17-13(11-7-3-1-4-8-11)15-16-14(18)12-9-5-2-6-10-12/h1-10H,(H,15,17)(H,16,18)
    Key: GRRIYLZJLGTQJX-UHFFFAOYSA-N
  • C1=CC=C(C=C1)C(=O)NNC(=O)C2=CC=CC=C2
Properties
C14H12N2O2
Molar mass 240.262 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Tebufenozide, methoxyfenozide and halofenozide are classed as commercial DBHs.[3]

In 2013, a compound of the substance was tested with promising results against larvae of Anopheles gambiae, the major vector for human malaria.[3]

References
  1. "Ecdysone receptor ligand-binding domain structure", WO 2004106374 A1
  2. "Dibenzoylhydrazine compound and insecticide", JPH03145447A
  3. "A new dibenzoylhydrazine with insecticidal activity against Anopheles mosquito larvae", Pest Manag Sci. 2013 Jul;69(7):827-33. doi: 10.1002/ps.3441
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